Flow Chemistry Instrumentation at University of Graz

The Kappe Laboratories currently occupy ca. 200 m2 of well-equipped laboratory space at the Institute of Chemistry (IfC) at the University of Graz, sufficient to accommodate 15 researchers to have bench and office space. Fully renovated and dedicated laboratory space for 20 researchers will be available by March of 2018. The group is well-equipped with all standard analytical instrumentation for performing modern organic synthesis (HPLC-UV(DAD), LC-MS(ESI), GC-FID, GC-MS(EI), semi-preparative HPLC-UV, automated flash chromatography, etc.) and has access to a range of departmental equipment including a variety of high-field NMR instruments (700, 500 and 360 MHz) in addition to IR, UV, various high resolution mass spectrometers (e.g., Q-TOF LC-MS), and analytical instrumentation (ICP-MS).

We are able to work with controlled substances  and have access to dedicated laboratories designed to allow handling of highly potent substances (Occupational Exposure Banding Level 4).

Dedicated Flow Chemistry Equipment

Uniqsis FlowSyn, 2 Uniqsis Binary Pumping Modules, Uniqsis Coil Reactor Heater
Vapourtec E-Series with UV 150 Photoreactor (Hg lamp and LEDs)
Syrris Asia 330 and 110 Systems including FLLEX module
Thales H-Cube, H-Cube Pro and X-Cube Reactors
One-A Engineering Plug &Play Reactor (TU Graz)
4 HiTec Zang SyrDos High-pressure Syringe Pumps
7 Syrris Asia Syringe Pumps, 6 Knauer HPLC pumps, 2 Vapourtec SF10 peristaltic pumps
Swagelock, Vapourtec, Zaiput and Upchurch Scientific Backpressure regulators
Gas Loading Module (Thales), 5 Bronkhorst Mass Flow Meters
Zaiput Liquid/Liquid Separators and Teflon AF2400 Gas Loading Modules (Uniqsis)
Various home-built systems for special application (high-T/p, photochemistry)
PAT: Mettler Toledo ReactIR/FlowIR; UV, NIR, Raman probes (TU Graz and RCPE)

Flow Reactors Available from our Industrial Partners

Modular micro/millireactor platform (MMRS, Ehrfeld)
Labtrix START (Chemtrix)

Dedicated Microwave Reactors

Anton Paar Monowave 50, 400 and 450 single mode reactors
Biotage Initiator+ and CEM Discover single mode reactor