Flow Chemistry Instrumentation at University of Graz

The Kappe Laboratories occupy ca. 400 m2 of well-equipped state-of-the-art laboratory space at the Institute of Chemistry (IfC) at the University of Graz, sufficient to accommodate 25 researchers to have bench and office space. The group is well-equipped with all standard analytical instrumentation for performing organic synthesis (HPLC-UV(DAD), LC-MS(ESI), GC-FID, GC-MS(EI), semi-preparative HPLC-UV, automated flash chromatography, etc.) and has access to a range of departmental equipment including a variety of high-field NMR instruments (700, 500 and 360 MHz) in addition to IR, UV, various high resolution mass spectrometers (e.g., Q-TOF LC-MS), and analytical instrumentation (ICP-MS).

We are able to work with controlled substances  and have access to dedicated laboratories designed to allow handling of highly potent substances (Occupational Exposure Banding Level 4).


Dedicated Flow Chemistry Equipment

2 Uniqsis FlowSyn, 2 Uniqsis Binary Pumping Modules, Uniqsis Coil Reactor Heater
Vapourtec E-Series with UV 150 Photoreactor (Hg lamp and LEDs)
Syrris Asia 330 and 110 Systems including FLLEX module
Thales H-Cube, H-Cube Pro and Phoenix Pro Flow Reactor

Ehrfeld Mikrosystem Modular micro/millireactor platform (MMRS)
Lonza FlowPlates
Chemtrix Protrix SiC Reactor
Corning Lab Photo Reactor

8 HiTec Zang SyrDos High-pressure Syringe Pumps
10 Syrris Asia Syringe Pumps, 6 Knauer HPLC pumps, 2 Vapourtec SF10 peristaltic pumps
Swagelock, Vapourtec, Zaiput and Upchurch Scientific Backpressure regulators
2 Gas Loading Module (Thales), 8 Bronkhorst Mass Flow Meters
3 Zaiput Liquid/Liquid Separators and Teflon AF2400 Gas Loading Modules (Uniqsis)

Process Analytical Technology (PAT)

2 Mettler Toledo ReactIR/FlowIRs
Magritek Spinsolve 43 Flow NMR
Shimadzu Nexera X2 UHPLC
AVASPEC-ULS2048-UV/vis-spectrometer
NIR, Raman probes (TU Graz and RCPE)

Dedicated Microwave Reactors

Anton Paar Monowave 50, 400 and 450 single mode reactors
Biotage Initiator+ and CEM Discover single mode reactor