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Recent Hot Papers from the Kappe Lab



Electrochemical Self-Optimization for the Synthesis of Densely Functionalized Molecules
E. Rial-Rodrígueza, F. Wagner, T. Fuchß, A. Sommer, J. Krieger, H.-M. Eggenweiler, C. O. Kappe, G. Laudadio,
Chem 2026, 12, 102952.
DOI: 10.1016j.chempr.2026.102952.

Scale-Up of Mechanochemical Amidation in Agitator Bead Mills: From Laboratory to Commercial Scale
K. Banderob, P. M. C. Roth, P. Caboni, C. O. Kappe, S. B. Ötvös,
Org. Process Res. Dev. 2026, 30, 2511−2519.
DOI: 10.1021/acs.oprd.6c00203.

Automated Dynamic Flow Experimentation for Rapid Kinetic Fitting of Transition Metal Catalysis
F. L. Wagner, K. Silber, T. A. Doliner, C. O. Kappe,
Angew. Chem. Int. Ed. 2026, 65, e6944441.
DOI: 10.1002/anie.6944441