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Recent Hot Papers from the Kappe Lab



Electrochemical Self-Optimization for the Synthesis of Densely Functionalized Molecules
E. Rial-Rodrígueza, F. Wagner, T. Fuchß, A. Sommer, J. Krieger, H.-M. Eggenweiler, C. O. Kappe, G. Laudadio,
Chem 2026, 12, in press.
DOI: 10.1016/j.chempr.2025.102875.

Scalable Mechanochemical Synthesis of Amides Using Bead Milling Technology
P. Caboni, A. Porcheddu, S. B. Ötvös, C. O. Kappe,
Green Chem. 2026, 28, in press.
DOI: 10.1039/D5GC04764A.

Leveraging an Intelligent Slug Flow Platform for Self-optimization of Reaction Systems with Categorical Variables
F. Wagner, G. Neun, T. Tampone, Z. Lei, F. Buono, C. A. Hone, C. O. Kappe,
Chem. Sci. 2025, 16, 22447–22455.
DOI: 10.1039/D5SC04715C